GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells

Somatic mutations in GNAQ gene were described as being the main oncogenic activation in uveal melanomas, whereas mutations in BRAF gene have been described as a key genetic alteration that contributes to skin melanoma development. We have previously reported differential activation of the MAPK and A...

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Detalles Bibliográficos
Autores principales: Pópulo, Helena, Tavares, Sandra, Faustino, Alexandra, Nunes, Joana B., Lopes, José Manuel, Soares, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728761/
https://www.ncbi.nlm.nih.gov/pubmed/23904987
http://dx.doi.org/10.7717/peerj.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728761/
https://www.ncbi.nlm.nih.gov/pubmed/23904987
http://dx.doi.org/10.7717/peerj.104

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