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A Polymorphism within the Promoter of the Dopamine Receptor D1 (DRD1 -48A/G) Associates with Impaired Kidney Function in White Hypertensive Patients

Dopamine DRD1 receptor regulates renal function and vascular resistance. It plays a role in the pathogenesis of hypertension in animal models. In humans, the DRD1 gene presents a A-48G polymorphism associated to hypertension in a Japanese population. To explore the role of this polymorphism on blood...

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Detalles Bibliográficos
Autores principales: Cipolletta, Ersilia, Ciccarelli, Michele, Izzo, Raffaele, Finelli, Rosa, Trimarco, Bruno, Iaccarino, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università di Salerno 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3728780/
https://www.ncbi.nlm.nih.gov/pubmed/23905040