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Exploitation of the IDO Pathway in the Therapy of Rheumatoid Arthritis
Indoleamine 2,3-dioxygenase (IDO) is the first and rate-limiting step along the kynurenine pathway and is thought to play a key role in immune homeostasis through depletion of tryptophan and accumulation of kynurenines. In this review we summarize recent research into the possibility of harnessing t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729277/ https://www.ncbi.nlm.nih.gov/pubmed/23922504 http://dx.doi.org/10.4137/IJTR.S11737 |