Determination of l-tryptophan and l-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS

Concentrations of l-tryptophan (l-Trp) and its metabolite, l-kynurenine (l-KYN), in sera of 19 normal subjects (age: 23.6 ± 3.5 y, male: 8, female: 11) were determined by high-performance liquid chromatography with mass-spectrometric detection, following their derivatization with (R)-(−)-4-(N, N-dim...

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Detalles Bibliográficos
Autores principales: Ohashi, Hayato, Iizuka, Hideaki, Yoshihara, Shunsuke, Otani, Hayato, Kume, Misato, Sadamoto, Kiyomi, Ichiba, Hideaki, Fukushima, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729339/
https://www.ncbi.nlm.nih.gov/pubmed/23922499
http://dx.doi.org/10.4137/IJTR.S11459

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729339/
https://www.ncbi.nlm.nih.gov/pubmed/23922499
http://dx.doi.org/10.4137/IJTR.S11459

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