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Determination of l-tryptophan and l-kynurenine in Human Serum by using LC-MS after Derivatization with (R)-DBD-PyNCS
Concentrations of l-tryptophan (l-Trp) and its metabolite, l-kynurenine (l-KYN), in sera of 19 normal subjects (age: 23.6 ± 3.5 y, male: 8, female: 11) were determined by high-performance liquid chromatography with mass-spectrometric detection, following their derivatization with (R)-(−)-4-(N, N-dim...
Autores principales: | Ohashi, Hayato, Iizuka, Hideaki, Yoshihara, Shunsuke, Otani, Hayato, Kume, Misato, Sadamoto, Kiyomi, Ichiba, Hideaki, Fukushima, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729339/ https://www.ncbi.nlm.nih.gov/pubmed/23922499 http://dx.doi.org/10.4137/IJTR.S11459 |
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