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Large-cell neuroendocrine carcinoma of lung with epidermal growth factor receptor (EGFR) gene mutation and co-expression of adenocarcinoma markers: a case report and review of the literature

PURPOSE: A high rate of response to treatment with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) has been observed in certain patients (women, of East Asian ethnicity, with non-smoking history and adenocarcinoma histology) with mutations in exons 18 to 21 of the tyrosine kina...

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Detalles Bibliográficos
Autores principales: Sakai, Yasuhiro, Yamasaki, Takashi, Kusakabe, Yoshito, Kasai, Daisuke, Kotani, Yoshikazu, Nishimura, Yoshihiro, Itoh, Tomoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729439/
https://www.ncbi.nlm.nih.gov/pubmed/23866929
http://dx.doi.org/10.1186/2049-6958-8-47