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Competence-Independent Activity of Pneumococcal Enda Mediates Degradation of Extracellular DNA and Nets and Is Important for Virulence

Membrane surface localized endonuclease EndA of the pulmonary pathogen Streptococcus pneumoniae (pneumococcus) is required for both genetic transformation and virulence. Pneumococcus expresses EndA during growth. However, it has been reported that EndA has no access to external DNA when pneumococcal...

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Detalles Bibliográficos
Autores principales: Zhu, Luchang, Kuang, Zhizhou, Wilson, Brenda A., Lau, Gee W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729463/
https://www.ncbi.nlm.nih.gov/pubmed/23936195
http://dx.doi.org/10.1371/journal.pone.0070363