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Spica prunellae promotes cancer cell apoptosis, inhibits cell proliferation and tumor angiogenesis in a mouse model of colorectal cancer via suppression of stat3 pathway

BACKGROUND: Constitutive activation of STAT3 is one of the major oncogenic pathways involved in the development of various types of malignancies including colorectal cancer (CRC); and thus becomes a promising therapeutic target. Spica Prunellae has long been used as an important component in many tr...

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Detalles Bibliográficos
Autores principales: Lin, Wei, Zheng, Liangpu, Zhuang, Qunchuan, Zhao, Jinyan, Cao, Zhiyun, Zeng, Jianwei, Lin, Shan, Xu, Wei, Peng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729539/
https://www.ncbi.nlm.nih.gov/pubmed/23800091
http://dx.doi.org/10.1186/1472-6882-13-144