The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors

The sensitivity of only a few tumors to anti-epidermal growth factor receptor EGFR tyrosine kinase inhibitors (TKIs) can be explained by the presence of EGFR tyrosine kinase (TK) domain mutations. In addition, such mutations were rarely found in tumor types other than lung, such as pancreatic and he...

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Detalles Bibliográficos
Autores principales: Chang, Xiaofei, Izumchenko, Eugene, Solis, Luisa M., Kim, Myoung Sook, Chatterjee, Aditi, Ling, Shizhang, Monitto, Constance L., Harari, Paul M., Hidalgo, Manuel, Goodman, Steve N., Wistuba, Ignacio I., Bedi, Atul, Sidransky, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729565/
https://www.ncbi.nlm.nih.gov/pubmed/23935914
http://dx.doi.org/10.1371/journal.pone.0068966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729565/
https://www.ncbi.nlm.nih.gov/pubmed/23935914
http://dx.doi.org/10.1371/journal.pone.0068966

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