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The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors
The sensitivity of only a few tumors to anti-epidermal growth factor receptor EGFR tyrosine kinase inhibitors (TKIs) can be explained by the presence of EGFR tyrosine kinase (TK) domain mutations. In addition, such mutations were rarely found in tumor types other than lung, such as pancreatic and he...
Autores principales: | Chang, Xiaofei, Izumchenko, Eugene, Solis, Luisa M., Kim, Myoung Sook, Chatterjee, Aditi, Ling, Shizhang, Monitto, Constance L., Harari, Paul M., Hidalgo, Manuel, Goodman, Steve N., Wistuba, Ignacio I., Bedi, Atul, Sidransky, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729565/ https://www.ncbi.nlm.nih.gov/pubmed/23935914 http://dx.doi.org/10.1371/journal.pone.0068966 |
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