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APOBEC3 inhibits DEAD-END function to regulate microRNA activity

The RNA binding protein DEAD-END (DND1) is one of the few proteins known to regulate microRNA (miRNA) activity at the level of miRNA-mRNA interaction. DND1 blocks miRNA interaction with the 3′-untranslated region (3′-UTR) of specific mRNAs and restores protein expression. Previously, we showed that...

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Detalles Bibliográficos
Autores principales: Ali, Sara, Karki, Namrata, Bhattacharya, Chitralekha, Zhu, Rui, MacDuff, Donna A, Stenglein, Mark D, Schumacher, April J, Demorest, Zachary L, Harris, Reuben S, Matin, Angabin, Aggarwal, Sita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729616/
https://www.ncbi.nlm.nih.gov/pubmed/23890083
http://dx.doi.org/10.1186/1471-2199-14-16