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HIV DNA Reservoir Increases Risk for Cognitive Disorders in cART-Naïve Patients

OBJECTIVES: Cognitive impairment remains frequent in HIV, despite combination antiretroviral therapy (cART). Leading theories implicate peripheral monocyte HIV DNA reservoirs as a mechanism for spread of the virus to the brain. These reservoirs remain present despite cART. The objective of this stud...

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Detalles Bibliográficos
Autores principales: Valcour, Victor G., Ananworanich, Jintanat, Agsalda, Melissa, Sailasuta, Napapon, Chalermchai, Thep, Schuetz, Alexandra, Shikuma, Cecilia, Liang, Chin-Yuan, Jirajariyavej, Supunee, Sithinamsuwan, Pasiri, Tipsuk, Somporn, Clifford, David B., Paul, Robert, Fletcher, James L. K., Marovich, Mary A., Slike, Bonnie M., DeGruttola, Victor, Shiramizu, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729685/
https://www.ncbi.nlm.nih.gov/pubmed/23936155
http://dx.doi.org/10.1371/journal.pone.0070164