Cargando…

Crucial Residue Involved in L-Lactate Recognition by Human Monocarboxylate Transporter 4 (hMCT4)

BACKGROUND: Monocarboxylate transporters (MCTs) transport monocarboxylates such as lactate, pyruvate and ketone bodies. These transporters are very attractive therapeutic targets in cancer. Elucidations of the functions and structures of MCTs is necessary for the development of effective medicine wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasaki, Shotaro, Kobayashi, Masaki, Futagi, Yuya, Ogura, Jiro, Yamaguchi, Hiroaki, Takahashi, Natsuko, Iseki, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729688/
https://www.ncbi.nlm.nih.gov/pubmed/23935841
http://dx.doi.org/10.1371/journal.pone.0067690