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Molecular Threading: Mechanical Extraction, Stretching and Placement of DNA Molecules from a Liquid-Air Interface

We present “molecular threading”, a surface independent tip-based method for stretching and depositing single and double-stranded DNA molecules. DNA is stretched into air at a liquid-air interface, and can be subsequently deposited onto a dry substrate isolated from solution. The design of an appara...

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Detalles Bibliográficos
Autores principales: Payne, Andrew C., Andregg, Michael, Kemmish, Kent, Hamalainen, Mark, Bowell, Charlotte, Bleloch, Andrew, Klejwa, Nathan, Lehrach, Wolfgang, Schatz, Ken, Stark, Heather, Marblestone, Adam, Church, George, Own, Christopher S., Andregg, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729692/
https://www.ncbi.nlm.nih.gov/pubmed/23935923
http://dx.doi.org/10.1371/journal.pone.0069058