Cargando…

Modulation of Pleurodeles waltl DNA Polymerase mu Expression by Extreme Conditions Encountered during Spaceflight

DNA polymerase µ is involved in DNA repair, V(D)J recombination and likely somatic hypermutation of immunoglobulin genes. Our previous studies demonstrated that spaceflight conditions affect immunoglobulin gene expression and somatic hypermutation frequency. Consequently, we questioned whether Polμ...

Descripción completa

Detalles Bibliográficos
Autores principales: Schenten, Véronique, Guéguinou, Nathan, Baatout, Sarah, Frippiat, Jean-Pol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729694/
https://www.ncbi.nlm.nih.gov/pubmed/23936065
http://dx.doi.org/10.1371/journal.pone.0069647