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Modulation of Pleurodeles waltl DNA Polymerase mu Expression by Extreme Conditions Encountered during Spaceflight
DNA polymerase µ is involved in DNA repair, V(D)J recombination and likely somatic hypermutation of immunoglobulin genes. Our previous studies demonstrated that spaceflight conditions affect immunoglobulin gene expression and somatic hypermutation frequency. Consequently, we questioned whether Polμ...
Autores principales: | Schenten, Véronique, Guéguinou, Nathan, Baatout, Sarah, Frippiat, Jean-Pol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729694/ https://www.ncbi.nlm.nih.gov/pubmed/23936065 http://dx.doi.org/10.1371/journal.pone.0069647 |
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