Conformational Stability of Fibrillar Amyloid-Beta Oligomers via Protofilament Pair Formation – A Systematic Computational Study

Amyloid-[Image: see text] (A[Image: see text]) oligomers play a crucial role in Alzheimer’s disease due to their neurotoxic aggregation properties. Fibrillar A[Image: see text] oligomerization can lead to protofilaments and protofilament pairs via oligomer elongation and oligomer association, respec...

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Detalles Bibliográficos
Autores principales: Kahler, Anna, Sticht, Heinrich, Horn, Anselm H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729696/
https://www.ncbi.nlm.nih.gov/pubmed/23936224
http://dx.doi.org/10.1371/journal.pone.0070521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729696/
https://www.ncbi.nlm.nih.gov/pubmed/23936224
http://dx.doi.org/10.1371/journal.pone.0070521

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