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Monoclonal antibody humanness score and its applications

BACKGROUND: Monoclonal antibody therapeutics are rapidly gaining in popularity for the treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and neurological diseases. Multiple forms of antibody therapeutics are in use today that differ in the amount of human sequence present...

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Detalles Bibliográficos
Autores principales: Gao, Sean H, Huang, Kexin, Tu, Hua, Adler, Adam S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729710/
https://www.ncbi.nlm.nih.gov/pubmed/23826749
http://dx.doi.org/10.1186/1472-6750-13-55