GFAP expression and social deficits in transgenic mice overexpressing human sAPPα

Autistic individuals display impaired social interactions and language, and restricted, stereotyped behaviors. Elevated levels of secreted amyloid precursor protein-alpha (sAPPα), the product of α-secretase cleavage of APP, are found in the plasma of some individuals with autism. The sAPPα protein i...

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Detalles Bibliográficos
Autores principales: Bailey, Antoinette R, Hou, Huayan, Song, Min, Obregon, Demian F, Portis, Samantha, Barger, Steven, Shytle, Doug, Stock, Saundra, Mori, Takashi, Sanberg, Paul G, Murphy, Tanya, Tan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729742/
https://www.ncbi.nlm.nih.gov/pubmed/23840007
http://dx.doi.org/10.1002/glia.22544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729742/
https://www.ncbi.nlm.nih.gov/pubmed/23840007
http://dx.doi.org/10.1002/glia.22544

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