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ACE-inhibition, but not weight reduction restores cardiomyocyte response to β-adrenergic stimulation in the metabolic syndrome

BACKGROUND: Diabetic cardiomyopathy is characterized by systolic and early diastolic ventricular dysfunction. In the metabolic syndrome (MS), ventricular stiffness is additionally increased in a later stage. It is unknown whether this is related to intrinsic cardiomyocyte dysfunction, extrinsic fact...

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Detalles Bibliográficos
Autores principales: Nevelsteen, Ines, Bito, Virginie, Van der Mieren, Gerry, Vanderper, Annelies, Van den Bergh, An, Sipido, Karin R, Mubagwa, Kanigula, Herijgers, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729821/
https://www.ncbi.nlm.nih.gov/pubmed/23848952
http://dx.doi.org/10.1186/1471-2261-13-51