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ACE-inhibition, but not weight reduction restores cardiomyocyte response to β-adrenergic stimulation in the metabolic syndrome
BACKGROUND: Diabetic cardiomyopathy is characterized by systolic and early diastolic ventricular dysfunction. In the metabolic syndrome (MS), ventricular stiffness is additionally increased in a later stage. It is unknown whether this is related to intrinsic cardiomyocyte dysfunction, extrinsic fact...
Autores principales: | Nevelsteen, Ines, Bito, Virginie, Van der Mieren, Gerry, Vanderper, Annelies, Van den Bergh, An, Sipido, Karin R, Mubagwa, Kanigula, Herijgers, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729821/ https://www.ncbi.nlm.nih.gov/pubmed/23848952 http://dx.doi.org/10.1186/1471-2261-13-51 |
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