Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells

Protein kinase CK2 is frequently elevated in a variety of human cancers. The Notch1 signalling pathway has been implicated in stem cell maintenance and its aberrant activation has been shown in several types of cancer including lung cancer. Here, we show, for the first time, that CK2α is a positive...

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Detalles Bibliográficos
Autores principales: Zhang, Shulin, Long, Hao, Yang, Yi-Lin, Wang, Yucheng, Hsieh, David, Li, Weiming, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729857/
https://www.ncbi.nlm.nih.gov/pubmed/23651443
http://dx.doi.org/10.1111/jcmm.12068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729857/
https://www.ncbi.nlm.nih.gov/pubmed/23651443
http://dx.doi.org/10.1111/jcmm.12068

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