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Inhibition of CK2α down-regulates Notch1 signalling in lung cancer cells
Protein kinase CK2 is frequently elevated in a variety of human cancers. The Notch1 signalling pathway has been implicated in stem cell maintenance and its aberrant activation has been shown in several types of cancer including lung cancer. Here, we show, for the first time, that CK2α is a positive...
Autores principales: | Zhang, Shulin, Long, Hao, Yang, Yi-Lin, Wang, Yucheng, Hsieh, David, Li, Weiming, Au, Alfred, Stoppler, Hubert J, Xu, Zhidong, Jablons, David M, You, Liang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729857/ https://www.ncbi.nlm.nih.gov/pubmed/23651443 http://dx.doi.org/10.1111/jcmm.12068 |
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