Conserved Roles of the Prion Protein Domains on Subcellular Localization and Cell-Cell Adhesion

Analyses of cultured cells and transgenic mice expressing prion protein (PrP) deletion mutants have revealed that some properties of PrP -such as its ability to misfold, aggregate and trigger neurotoxicity- are controlled by discrete molecular determinants within its protein domains. Although the co...

Descripción completa

Detalles Bibliográficos
Autores principales: Solis, Gonzalo P., Radon, Yvonne, Sempou, Emily, Jechow, Katharina, Stuermer, Claudia A. O., Málaga-Trillo, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729945/
https://www.ncbi.nlm.nih.gov/pubmed/23936187
http://dx.doi.org/10.1371/journal.pone.0070327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729945/
https://www.ncbi.nlm.nih.gov/pubmed/23936187
http://dx.doi.org/10.1371/journal.pone.0070327

Ejemplares similares