NSun2-Mediated Cytosine-5 Methylation of Vault Noncoding RNA Determines Its Processing into Regulatory Small RNAs

Autosomal-recessive loss of the NSUN2 gene has been identified as a causative link to intellectual disability disorders in humans. NSun2 is an RNA methyltransferase modifying cytosine-5 in transfer RNAs (tRNAs), yet the identification of cytosine methylation in other RNA species has been hampered by...

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Detalles Bibliográficos
Autores principales: Hussain, Shobbir, Sajini, Abdulrahim A., Blanco, Sandra, Dietmann, Sabine, Lombard, Patrick, Sugimoto, Yoichiro, Paramor, Maike, Gleeson, Joseph G., Odom, Duncan T., Ule, Jernej, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730056/
https://www.ncbi.nlm.nih.gov/pubmed/23871666
http://dx.doi.org/10.1016/j.celrep.2013.06.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730056/
https://www.ncbi.nlm.nih.gov/pubmed/23871666
http://dx.doi.org/10.1016/j.celrep.2013.06.029

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