Proximal tubule specific knockout of the Na(+)/H(+) exchanger NHE3: effects on bicarbonate absorption and ammonium excretion

The existing NHE3 knockout mouse has significant intestinal electrolyte absorption defects, making this model unsuitable for the examination of the role of proximal tubule NHE3 in pathophysiologic states in vivo. To overcome this problem, we generated proximal convoluted tubule-specific KO mice (NHE...

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Detalles Bibliográficos
Autores principales: Li, Hong C., Du, Zhaopeng, Barone, Sharon, Rubera, Isabelle, McDonough, Alicia A., Tauc, Michel, Zahedi, Kamyar, Wang, Tong, Soleimani, Manoocher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730089/
https://www.ncbi.nlm.nih.gov/pubmed/23508938
http://dx.doi.org/10.1007/s00109-013-1015-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730089/
https://www.ncbi.nlm.nih.gov/pubmed/23508938
http://dx.doi.org/10.1007/s00109-013-1015-3

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