Integrin α5β1, the Fibronectin Receptor, as a Pertinent Therapeutic Target in Solid Tumors

Integrins are transmembrane heterodimeric proteins sensing the cell microenvironment and modulating numerous signalling pathways. Changes in integrin expression between normal and tumoral cells support involvement of specific integrins in tumor progression and aggressiveness. This review highlights...

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Detalles Bibliográficos
Autores principales: Schaffner, Florence, Ray, Anne Marie, Dontenwill, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730317/
https://www.ncbi.nlm.nih.gov/pubmed/24216697
http://dx.doi.org/10.3390/cancers5010027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730317/
https://www.ncbi.nlm.nih.gov/pubmed/24216697
http://dx.doi.org/10.3390/cancers5010027

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