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Global Decrease of Histone H3K27 Acetylation in ZEB1-Induced Epithelial to Mesenchymal Transition in Lung Cancer Cells

The epithelial to mesenchymal transition (EMT) enables epithelial cells with a migratory mesenchymal phenotype. It is activated in cancer cells and is involved in invasion, metastasis and stem-like properties. ZEB1, an E-box binding transcription factor, is a major suppressor of epithelial genes in...

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Detalles Bibliográficos
Autores principales: Roche, Joëlle, Nasarre, Patrick, Gemmill, Robert, Baldys, Aleksander, Pontis, Julien, Korch, Christopher, Guilhot, Joëlle, Ait-Si-Ali, Slimane, Drabkin, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730320/
https://www.ncbi.nlm.nih.gov/pubmed/24216980
http://dx.doi.org/10.3390/cancers5020334