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Molecular Imaging of Nonsmall Cell Lung Carcinomas Expressing Active Mutant EGFR Kinase Using PET with [(124)I]-Morpholino-IPQA

Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]...

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Detalles Bibliográficos
Autores principales: Yeh, Skye Hsin-Hsien, Lin, Chien-Feng, Kong, Fan-Lin, Wang, Hsin-Ell, Hsieh, Ya-Ju, Gelovani, Juri G., Liu, Ren-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730369/
https://www.ncbi.nlm.nih.gov/pubmed/23956990
http://dx.doi.org/10.1155/2013/549359