Cargando…

Molecular Imaging of Nonsmall Cell Lung Carcinomas Expressing Active Mutant EGFR Kinase Using PET with [(124)I]-Morpholino-IPQA

Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeh, Skye Hsin-Hsien, Lin, Chien-Feng, Kong, Fan-Lin, Wang, Hsin-Ell, Hsieh, Ya-Ju, Gelovani, Juri G., Liu, Ren-Shyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730369/ https://www.ncbi.nlm.nih.gov/pubmed/23956990 http://dx.doi.org/10.1155/2013/549359

Ejemplares similares

In Vivo Evaluation of the Combined Anticancer Effects of Cisplatin and SAHA in Nonsmall Cell Lung Carcinoma Using [(18)F]FAHA and [(18)F]FDG PET/CT Imaging
por: Yeh, Skye Hsin-Hsien, et al.
Publicado: (2021)

Rational Design of a Triple Reporter Gene for Multimodality Molecular Imaging
por: Hsieh, Ya-Ju, et al.
Publicado: (2014)

In Vivo 6-([(18)F]Fluoroacetamido)-1-hexanoicanilide PET Imaging of Altered Histone Deacetylase Activity in Chemotherapy-Induced Neurotoxicity
por: Fukumitsu, Nobuyoshi, et al.
Publicado: (2018)

Evaluation of Inhibitory Effect of Recreational Drugs on Dopaminergic Terminal Neuron by PET and Whole-Body Autoradiography
por: Yeh, Skye Hsin-Hsien, et al.
Publicado: (2014)

Monitoring Therapy with MEK Inhibitor U0126 in a Novel Wilms Tumor Model in Wt1 Knockout Igf2 Transgenic Mice Using (18)F-FDG PET with Dual-Contrast Enhanced CT and MRI: Early Metabolic Response Without Inhibition of Tumor Growth
por: Flores, Leo G., et al.
Publicado: (2012)

Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment
por: Kuo, Wei-Ying, et al.
Publicado: (2015)

Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
por: Place, Elsie S., et al.
Publicado: (2017)

Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes
por: Eve, Alexander M. J., et al.
Publicado: (2017)

Correction: Zebrafish atoh8 mutants do not recapitulate morpholino phenotypes
por: Place, Elsie S., et al.
Publicado: (2017)

The peripheral blood neutrophil-to-lymphocyte ratio is a prognostic predictor for survival of EGFR-mutant nonsmall cell lung cancer patients treated with EGFR-TKIs
por: Zhang, Yuan, et al.
Publicado: (2018)

Synthesis and Preclinical Characterization of [(18)F]FPBZA: A Novel PET Probe for Melanoma
por: Wu, Shih-Yen, et al.
Publicado: (2014)

GMP-compliant fully automated radiosynthesis of [(18)F]FEPPA for PET/MRI imaging of regional brain TSPO expression
por: Chang, Chi-Wei, et al.
Publicado: (2021)

Detection of Pancreatic Carcinomas by Imaging Lactose-Binding Protein Expression in Peritumoral Pancreas Using [(18)F]Fluoroethyl-Deoxylactose PET/CT
por: Flores, Leo Garcia, et al.
Publicado: (2009)

Amitriptyline Accelerates SERT Binding Recovery in a Rat 3,4-Methylenedioxymethamphetamine (MDMA) Model: In Vivo 4-[(18)F]-ADAM PET Imaging
por: Tsai, Chi-Jung, et al.
Publicado: (2022)

Icotinib and whole-brain radiotherapy for the treatment in patients with brain metastases from EGFR-mutant nonsmall cell lung cancer: A retrospective study
por: Jiang, Ai-Ying, et al.
Publicado: (2018)

Guidelines for morpholino use in zebrafish
por: Stainier, Didier Y. R., et al.
Publicado: (2017)

Lysine Deprivation Induces AKT-AADAT Signaling and Overcomes EGFR-TKIs Resistance in EGFR-Mutant Non-Small Cell Lung Cancer Cells
por: Hsu, Chia-Chi, et al.
Publicado: (2021)

Osimertinib or EGFR-TKIs/chemotherapy in patients with EGFR-mutated advanced nonsmall cell lung cancer: A meta-analysis
por: Huang, Lei, et al.
Publicado: (2019)

Development of Radiofluorinated Nicotinamide/Picolinamide Derivatives as Diagnostic Probes for the Detection of Melanoma
por: Lo, Yi-Hsuan, et al.
Publicado: (2021)

The content of mutant EGFR DNA correlates with response to EGFR-TKIs in lung adenocarcinoma patients with common EGFR mutations
por: Hung, Ming-Szu, et al.
Publicado: (2016)

Noninvasive quantification of SIRT1 expression–activity and pharmacologic inhibition in a rat model of intracerebral glioma using 2-[(18)F]BzAHA PET/CT/MRI
por: Laws, Maxwell T, et al.
Publicado: (2020)

Preliminary Results on the Long-Term Effects of Dextromethorphan on MDMA-Mediated Serotonergic Deficiency and Volumetric Changes in Primates Based on 4-[(18)F]-ADAM PET/MRI
por: Yeh, Skye Hsin-Hsien, et al.
Publicado: (2022)

Histological Transformation after Acquired Resistance to the Third-Generation EGFR-TKI in Patients with Advanced EGFR-Mutant Lung Adenocarcinoma
por: Lee, Po-Hsin, et al.
Publicado: (2022)

Pemetrexed/carboplatin plus gefitinib as a first-line treatment for EGFR-mutant advanced nonsmall cell lung cancer: a Bayesian network meta-analysis
por: Zhang, Zhonghan, et al.
Publicado: (2019)

Chloroquine Enhances Gefitinib Cytotoxicity in Gefitinib-Resistant Nonsmall Cell Lung Cancer Cells
por: Tang, Mei-Chuan, et al.
Publicado: (2015)

In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
por: Aung-Htut, May T., et al.
Publicado: (2019)

Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model
por: Lin, Liang-Ting, et al.
Publicado: (2016)

Multi-Modal Synergistic 99mTc-TRODAT-1 SPECT and MRI for Evaluation of the Efficacy of Hyperbaric Oxygen Therapy in CO-Induced Delayed Parkinsonian and Non-Parkinsonian Syndromes
por: Yeh, Skye Hsin-Hsien, et al.
Publicado: (2022)

Molecular imaging HDACs class IIa expression-activity and pharmacologic inhibition in intracerebral glioma models in rats using PET/CT/(MRI) with [(18)F]TFAHA
por: Laws, Maxwell T., et al.
Publicado: (2019)

Terpinen-4-ol Induces Apoptosis in Human Nonsmall Cell Lung Cancer In Vitro and In Vivo
por: Wu, Chieh-Shan, et al.
Publicado: (2012)

klf2a (sh317) Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes
por: Novodvorsky, Peter, et al.
Publicado: (2015)

Evaluation of the increase in permeability of the blood–brain barrier during tumor progression after pulsed focused ultrasound
por: Yang, Feng-Yi, et al.
Publicado: (2012)

Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives
por: Cheng, Xinghua, et al.
Publicado: (2014)

First-line treatment of EGFR-mutated nonsmall cell lung cancer: critical review on study methodology
por: Sebastian, Martin, et al.
Publicado: (2014)

Novel Histone Deacetylase Class IIa Selective Substrate Radiotracers for PET Imaging of Epigenetic Regulation in the Brain
por: Bonomi, Robin, et al.
Publicado: (2015)

Automated Synthesis and Initial Evaluation of (4′-Amino-5′,8′-difluoro-1′H-spiro[piperidine-4,2′-quinazolin]-1-yl)(4-[(18)F]fluorophenyl)methanone for PET/MR Imaging of Inducible Nitric Oxide Synthase
por: Yeh, Skye Hsin-Hsien, et al.
Publicado: (2021)

AMOD: a morpholino oligonucleotide selection tool
por: Klee, Eric W., et al.
Publicado: (2005)

Lessons from morpholino-based screening in zebrafish
por: Bedell, Victoria M., et al.
Publicado: (2011)

Versatile Synthesis and Rational Design of Caged Morpholinos
por: Ouyang, Xiaohu, et al.
Publicado: (2009)

In vivo Electroporation of Morpholinos into the Adult Zebrafish Retina
por: Thummel, Ryan, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_41apjbkm3pn2bsilapmnef4ivo