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Targeting cancer stem cells expressing an embryonic signature with anti-proteases to decrease their tumor potential

Cancer stem cells (CSCs) are a specific subset of cancer cells that sustain tumor growth and dissemination. They might represent a significant treatment target to reduce malignant progression and prevent tumor recurrence. In solid tumors, several hierarchically organized CSC clones coexist, even wit...

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Detalles Bibliográficos
Autores principales: Darini, C Y, Martin, P, Azoulay, S, Drici, M-D, Hofman, P, Obba, S, Dani, C, Ladoux, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730396/
https://www.ncbi.nlm.nih.gov/pubmed/23828569
http://dx.doi.org/10.1038/cddis.2013.206