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Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

Autophagy is an important cellular process that controls cells in a normal homeostatic state by recycling nutrients to maintain cellular energy levels for cell survival via the turnover of proteins and damaged organelles. However, persistent activation of autophagy can lead to excessive depletion of...

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Detalles Bibliográficos
Autores principales: Wong, V KW, Li, T, Law, B YK, Ma, E DL, Yip, N C, Michelangeli, F, Law, C KM, Zhang, M M, Lam, K YC, Chan, P L, Liu, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730398/
https://www.ncbi.nlm.nih.gov/pubmed/23846222
http://dx.doi.org/10.1038/cddis.2013.217