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Induction of inner ear hair cell-like cells from Math1-transfected mouse ES cells

Math1, a basic helix-loop-helix transcription factor homolog of the Drosophila atonal gene, is considered to be a key factor for induction of sensory hair cells (HCs) during development of the organ of Corti or cochlea. Although embryonic stem (ES) cells are able to produce HC-like cells, the role o...

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Detalles Bibliográficos
Autores principales: Ouji, Y, Ishizaka, S, Nakamura-Uchiyama, F, Wanaka, A, Yoshikawa, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730404/
https://www.ncbi.nlm.nih.gov/pubmed/23828563
http://dx.doi.org/10.1038/cddis.2013.230