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DAX-1, as an androgen-target gene, inhibits aromatase expression: a novel mechanism blocking estrogen-dependent breast cancer cell proliferation

Sexual hormones, estrogens and androgens, determine biological response in a tissue- and gender-specific manner and have a pivotal role in endocrine-mediated tumorigenesis. In situ estrogen production by aromatase is a critical determinant for breast cancer growth and progression. On the contrary, c...

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Detalles Bibliográficos
Autores principales: Lanzino, M, Maris, P, Sirianni, R, Barone, I, Casaburi, I, Chimento, A, Giordano, C, Morelli, C, Sisci, D, Rizza, P, Bonofiglio, D, Catalano, S, Andò, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730409/
https://www.ncbi.nlm.nih.gov/pubmed/23846226
http://dx.doi.org/10.1038/cddis.2013.235