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Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia
Microglia are the resident immune cells in the central nervous system and key players against pathogens and injury. However, persistent microglial activation often exacerbates pathological damage and has been implicated in many neurological diseases. Despite their pivotal physiological and pathophys...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730412/ https://www.ncbi.nlm.nih.gov/pubmed/23846218 http://dx.doi.org/10.1038/cddis.2013.238 |