RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells

RhoA GTPase dysregulation is frequently reported in various tumours and haematologic malignancies. RhoA, regulating Rho-associated coiled-coil-forming kinase 1 (ROCK1), modulates multiple cell functions, including malignant transformation, metastasis and cell death. Therefore, RhoA/ROCK1 could be an...

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Detalles Bibliográficos
Autores principales: Li, F, Jiang, Q, Shi, K J, Luo, H, Yang, Y, Xu, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730416/
https://www.ncbi.nlm.nih.gov/pubmed/23828571
http://dx.doi.org/10.1038/cddis.2013.243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730416/
https://www.ncbi.nlm.nih.gov/pubmed/23828571
http://dx.doi.org/10.1038/cddis.2013.243

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