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Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing
Despite remarkable efforts, metastatic melanoma (MM) still presents with significant mortality. Recently, mono-chemotherapies are increasingly replenished by more cancer-specific combination therapies involving death ligands and drugs interfering with cell signaling. Still, MM remains a fatal diseas...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730422/ https://www.ncbi.nlm.nih.gov/pubmed/23846221 http://dx.doi.org/10.1038/cddis.2013.249 |