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Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing

Despite remarkable efforts, metastatic melanoma (MM) still presents with significant mortality. Recently, mono-chemotherapies are increasingly replenished by more cancer-specific combination therapies involving death ligands and drugs interfering with cell signaling. Still, MM remains a fatal diseas...

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Detalles Bibliográficos
Autores principales: Vörsmann, H, Groeber, F, Walles, H, Busch, S, Beissert, S, Walczak, H, Kulms, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730422/
https://www.ncbi.nlm.nih.gov/pubmed/23846221
http://dx.doi.org/10.1038/cddis.2013.249