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A rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation

The complexity of many RNA processing pathways is such that a conventional systems modelling approach is inadequate to represent all the molecular species involved. We demonstrate that rule-based modelling permits a detailed model of a complex RNA signalling pathway to be defined. Phosphorylation of...

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Detalles Bibliográficos
Autores principales: Aitken, Stuart, Alexander, Ross D., Beggs, Jean D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730697/
https://www.ncbi.nlm.nih.gov/pubmed/23804443
http://dx.doi.org/10.1098/rsif.2013.0438