T Cells Induce Pre-Metastatic Osteolytic Disease and Help Bone Metastases Establishment in a Mouse Model of Metastatic Breast Cancer

Bone metastases, present in 70% of patients with metastatic breast cancer, lead to skeletal disease, fractures and intense pain, which are all believed to be mediated by tumor cells. Engraftment of tumor cells is supposed to be preceded by changes in the target tissue to create a permissive microenv...

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Detalles Bibliográficos
Autores principales: Monteiro, Ana Carolina, Leal, Ana Carolina, Gonçalves-Silva, Triciana, Mercadante, Ana Carolina T., Kestelman, Fabiola, Chaves, Sacha Braun, Azevedo, Ricardo Bentes, Monteiro, João P., Bonomo, Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730734/
https://www.ncbi.nlm.nih.gov/pubmed/23935856
http://dx.doi.org/10.1371/journal.pone.0068171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730734/
https://www.ncbi.nlm.nih.gov/pubmed/23935856
http://dx.doi.org/10.1371/journal.pone.0068171

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