Synthetic glycopeptides reveal the glycan specificity of HIV-neutralizing antibodies

A new class of glycan-reactive HIV-neutralizing antibodies, including PG9 and PG16, has been recently discovered that appear to recognize novel glycopeptide epitopes on HIV-1 gp120. However, further characterization and reconstitution of the precise neutralizing epitopes are complicated by the heter...

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Detalles Bibliográficos
Autores principales: Amin, Mohammed N., McLellan, Jason S., Huang, Wei, Orwenyo, Jared, Burton, Dennis R., Koff, Wayne C., Kwong, Peter D., Wang, Lai-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730851/
https://www.ncbi.nlm.nih.gov/pubmed/23831758
http://dx.doi.org/10.1038/nchembio.1288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730851/
https://www.ncbi.nlm.nih.gov/pubmed/23831758
http://dx.doi.org/10.1038/nchembio.1288

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