Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling

Transfer RNA (tRNA) modifications enhance the efficiency, specificity and fidelity of translation in all organisms. The anticodon modification mcm(5)s(2)U(34) is required for normal growth and stress resistance in yeast; mutants lacking this modification have numerous phenotypes. Mutations in the ho...

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Detalles Bibliográficos
Autores principales: Zinshteyn, Boris, Gilbert, Wendy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731203/
https://www.ncbi.nlm.nih.gov/pubmed/23935536
http://dx.doi.org/10.1371/journal.pgen.1003675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731203/
https://www.ncbi.nlm.nih.gov/pubmed/23935536
http://dx.doi.org/10.1371/journal.pgen.1003675

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