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Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling
Transfer RNA (tRNA) modifications enhance the efficiency, specificity and fidelity of translation in all organisms. The anticodon modification mcm(5)s(2)U(34) is required for normal growth and stress resistance in yeast; mutants lacking this modification have numerous phenotypes. Mutations in the ho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731203/ https://www.ncbi.nlm.nih.gov/pubmed/23935536 http://dx.doi.org/10.1371/journal.pgen.1003675 |