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Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration

Calpains are Ca(2+)-dependent modulator Cys proteases that have a variety of functions in almost all eukaryotes. There are more than 10 well-conserved mammalian calpains, among which eutherian calpain-6 (CAPN6) is unique in that it has amino acid substitutions at the active-site Cys residue (to Lys...

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Detalles Bibliográficos
Autores principales: Tonami, Kazuo, Hata, Shoji, Ojima, Koichi, Ono, Yasuko, Kurihara, Yukiko, Amano, Tomokazu, Sato, Takahiro, Kawamura, Yumiko, Kurihara, Hiroki, Sorimachi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731218/
https://www.ncbi.nlm.nih.gov/pubmed/23935533
http://dx.doi.org/10.1371/journal.pgen.1003668