Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs

Genetic variants in cis-regulatory elements or trans-acting regulators frequently influence the quantity and spatiotemporal distribution of gene transcription. Recent interest in expression quantitative trait locus (eQTL) mapping has paralleled the adoption of genome-wide association studies (GWAS)...

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Detalles Bibliográficos
Autores principales: Brown, Christopher D., Mangravite, Lara M., Engelhardt, Barbara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731231/
https://www.ncbi.nlm.nih.gov/pubmed/23935528
http://dx.doi.org/10.1371/journal.pgen.1003649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731231/
https://www.ncbi.nlm.nih.gov/pubmed/23935528
http://dx.doi.org/10.1371/journal.pgen.1003649

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