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Discovery of Anthelmintic Drug Targets and Drugs Using Chokepoints in Nematode Metabolic Pathways

Parasitic roundworm infections plague more than 2 billion people (1/3 of humanity) and cause drastic losses in crops and livestock. New anthelmintic drugs are urgently needed as new drug resistance and environmental concerns arise. A “chokepoint reaction” is defined as a reaction that either consume...

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Detalles Bibliográficos
Autores principales: Taylor, Christina M., Wang, Qi, Rosa, Bruce A., Huang, Stanley Ching-Cheng, Powell, Kerrie, Schedl, Tim, Pearce, Edward J., Abubucker, Sahar, Mitreva, Makedonka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731235/
https://www.ncbi.nlm.nih.gov/pubmed/23935495
http://dx.doi.org/10.1371/journal.ppat.1003505