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A Novel Role for Pro-Coagulant Microvesicles in the Early Host Defense against Streptococcus pyogenes

Previous studies have shown that stimulation of whole blood or peripheral blood mononuclear cells with bacterial virulence factors results in the sequestration of pro-coagulant microvesicles (MVs). These particles explore their clotting activity via the extrinsic and intrinsic pathway of coagulation...

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Detalles Bibliográficos
Autores principales: Oehmcke, Sonja, Westman, Johannes, Malmström, Johan, Mörgelin, Matthias, Olin, Anders I., Kreikemeyer, Bernd, Herwald, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731245/
https://www.ncbi.nlm.nih.gov/pubmed/23935504
http://dx.doi.org/10.1371/journal.ppat.1003529