Clostridium difficile 027/BI/NAP1 Encodes a Hypertoxic and Antigenically Variable Form of TcdB

The Clostridium difficile exotoxin, TcdB, which is a major virulence factor, varies between strains of this pathogen. Herein, we show that TcdB from the epidemic BI/NAP1/027 strain of C. difficile is more lethal, causes more extensive brain hemorrhage, and is antigenically variable from TcdB produce...

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Detalles Bibliográficos
Autores principales: Lanis, Jordi M., Heinlen, Latisha D., James, Judith A., Ballard, Jimmy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731247/
https://www.ncbi.nlm.nih.gov/pubmed/23935501
http://dx.doi.org/10.1371/journal.ppat.1003523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731247/
https://www.ncbi.nlm.nih.gov/pubmed/23935501
http://dx.doi.org/10.1371/journal.ppat.1003523

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