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Post-Translational Control of IL-1β via the Human Papillomavirus Type 16 E6 Oncoprotein: A Novel Mechanism of Innate Immune Escape Mediated by the E3-Ubiquitin Ligase E6-AP and p53

Infections with high-risk human papillomaviruses (HPVs) are causally involved in the development of anogenital cancer. HPVs apparently evade the innate immune response of their host cells by dysregulating immunomodulatory factors such as cytokines and chemokines, thereby creating a microenvironment...

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Detalles Bibliográficos
Autores principales: Niebler, Martina, Qian, Xu, Höfler, Daniela, Kogosov, Vlada, Kaewprag, Jittranan, Kaufmann, Andreas M., Ly, Regina, Böhmer, Gerd, Zawatzky, Rainer, Rösl, Frank, Rincon-Orozco, Bladimiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731255/
https://www.ncbi.nlm.nih.gov/pubmed/23935506
http://dx.doi.org/10.1371/journal.ppat.1003536