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HIV-1 Tropism Testing in Subjects Achieving Undetectable HIV-1 RNA: Diagnostic Accuracy, Viral Evolution and Compartmentalization

BACKGROUND: Technically, HIV-1 tropism can be evaluated in plasma or peripheral blood mononuclear cells (PBMCs). However, only tropism testing of plasma HIV-1 has been validated as a tool to predict virological response to CCR5 antagonists in clinical trials. The preferable tropism testing strategy...

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Detalles Bibliográficos
Autores principales: Pou, Christian, Codoñer, Francisco M., Thielen, Alexander, Bellido, Rocío, Pérez-Álvarez, Susana, Cabrera, Cecilia, Dalmau, Judith, Curriu, Marta, Lie, Yolanda, Noguera-Julian, Marc, Puig, Jordi, Martínez-Picado, Javier, Blanco, Julià, Coakley, Eoin, Däumer, Martin, Clotet, Bonaventura, Paredes, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731261/
https://www.ncbi.nlm.nih.gov/pubmed/23936293
http://dx.doi.org/10.1371/journal.pone.0067085