TP53 and Let-7a micro-RNA Regulate K-Ras Activity in HCT116 Colorectal Cancer Cells

Recent reports have indicated that KRAS and TP53 mutations predict response to therapy in colorectal cancer. However, little is known about the relationship between these two common genetic alterations. Micro-RNAs (miRNAs), a class of noncoding RNA implicated in cellular processes, have been increas...

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Detalles Bibliográficos
Autores principales: Luu, Carrie, Heinrich, Eileen L., Duldulao, Marjun, Arrington, Amanda K., Fakih, Marwan, Garcia-Aguilar, Julio, Kim, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731270/
https://www.ncbi.nlm.nih.gov/pubmed/23936455
http://dx.doi.org/10.1371/journal.pone.0070604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731270/
https://www.ncbi.nlm.nih.gov/pubmed/23936455
http://dx.doi.org/10.1371/journal.pone.0070604

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